SOLVED: How To Setup User Isolation Mode in IIS FTP
After you have FTP setup in IIS, you might find that you want to be able to set each users FTP folder. To do this you need to set IIS FTP to run in USER ISOLATION MODE, and while this not hard, is it not obvious.
Add the FTP EXTENSIBILITY sub-role in SERVER MANAGER > ADD ROLES AND FEATURES
Create a file share on your network (i.e. \\DC1\TestFTPRoot\ )
Create subfolder(s) under that FTP (i.e. \CLIENTS\INVOICES)
In IIS click on FTP USER ISOLATION icon and then select FTP HOME DIRECTORY CONFIGURED IN ACTIVE DIRECTORY
In ACTIVE DIRECTORY USERS AND COMPUTERS, click VIEW menu, enable ADVANCED FEATURES
Double click on the user you want to set
Click ATTRIBUTE EDITOR tab
In msIIS-FTPRoot and set it to the shared folder you created in step 2 (i.e. \\DC1\TestFTPRoot\ )
In msIIS-FTPDir and set it to the shared folder you created in step 3 settings (i.e. \CLIENTS\INVOICES)
Restart your FTP site to have all the changes take effect