If you have tried to install Adobe Reader on Server 2012 you see an INTERNAL ERROR OCCURED message and when you click OK, Reader will terminate.
There are two ways around this that I know of:
Officially Adobe says Server 2012 is NOT supported for Adobe Reader. See THIS Adobe article.
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Most likely the problem is related to the use of User Profile Disks on RD Session Host server.
As a workaround, you can turn off safe mode in Adobe Reader. But disabling safe mode in Adobe Reader is not a good idea for a multi-user environment.
As an alternative, you can use Foxit Reader (it's free without the use of plug-ins). It works fine.
http://blog.it-kb.ru/2014/09/03/adobe-reader-and-rds-upd-an-internal-error-occurred-and-gpo-settins-for-alternative-free-pdf-viewer-foxit-reader-enterprise/